Symbol Name ID |
Unc13d
unc-13 homolog D MGI:1917700 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Reduced natural killer cell activity |
Anemia |
Granulocytopenia |
Hemophagocytosis |
Hypofibrinogenemia |
Hepatosplenomegaly |
Disease(s) Associated with UNC13D | ||||||
familial hemophagocytic lymphohistiocytosis 3 |
Mouse Phenotypes | hematopoietic system phenotype |
enlarged spleen |
anemia |
increased neutrophil cell number |
thrombocytopenia |
increased CD8-positive, alpha-beta T cell number |
increased monocyte cell number |
abnormal NK cell physiology |
decreased cytotoxic T cell cytolysis |
abnormal macrophage physiology |
hemophagocytosis |
decreased platelet aggregation |
abnormal platelet dense granule physiology |
|
Availability | Mouse Genotype | |||||||||||||
Unc13dJinx/Unc13dJinx | ||||||||||||||
Unc13dtm1(KOMP)Vlcg/Unc13dtm1(KOMP)Vlcg | * |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 04/30/2024 MGI 6.23 |
|
|